HR Generalist
Helix
People & HR
San Diego, CA, USA
USD 72k-104,250 / year + Equity
Posted on Oct 11, 2025
HR Generalist
San Diego, CA
Human Resources
Hybrid
Full-time
Who We Are & What We Do
At Helix, our mission is simple: to help everyone improve their lives through their DNA.
Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.
What is special about this role?
The HR Generalist plays a crucial and multifaceted role in the People team. This position will act as a dedicated HR Business Partner for our Lab Operations department based in San Diego, managing various aspects of the employee lifecycle/ providing general HR support, as well as providing critical operational support (approximately 50% of time) to the Recruiting function within our People team. This is an exciting opportunity for a tech-savvy, rising HR professional to gain broad experience and contribute to key People initiatives.
As an HR Generalist, you will:
HR Business Partner (Lab Operations)
- Develop a solid understanding of the business, build relationships with assigned client group, and create close partnerships across the organization
- Manage employee relations issues; with support from the HR Operations team
- Provide guidance and coach managers and other team members on HR policies and best practices
- Partner with managers on performance reviews, calibrations, and compensation discussions to ensure fairness in decision making
- Participate in the Recruiting process by reviewing requisitions for appropriate leveling and compensation
- Maintain accurate and up-to-date employee data in the HRIS systems (US and international), ensuring data integrity and confidentiality
Recruiting Support
- Execute proactive sourcing strategies using tools like LinkedIn Recruiter and our ATS (Gem) to build robust pipelines of qualified candidates for a variety of critical roles
- Conduct initial resume screening and in-depth profile reviews to evaluate candidates against technical requirements
- Orchestrate complex interview schedules across multiple time zones, ensuring a smooth and positive experience for both candidates and internal hiring teams
- Serve as the primary point of contact for candidates throughout the interview process, handling all logistical communications with a professional and welcoming demeanor
- Conduct preliminary phone or video interviews to assess foundational qualifications and candidate alignment
- Maintain pristine data integrity by managing and updating candidate information in Gem
- Contribute to employer branding initiatives and recruiting events as needed
- Partner with the recruiting team to enhance our hiring operations by identifying and implementing AI-driven tools and automations, boosting efficiency and data accuracy
People Programs & Project Support
- Participate in the evaluation and enhancement of HR processes to streamline operations and improve efficiency
- Leverage AI tools and technologies to optimize workflows, automate repetitive tasks, and enhance HR processes
Employee Lifecycle & General HR Support
- Provide back-up support to the HR Operations team in various aspects of the employee lifecycle, such as onboarding, offboarding, benefits and reporting
- Ensure compliance with data privacy regulations and company policies when handling sensitive HR data, and with applicable employment laws and regulations
Office Support
- Participate in the coordination of San Diego office activities when required
About you:
- Bachelor's degree in Human Resources, Business Administration, or a related field (or equivalent experience)
- 2+ years of experience in HR operations, HR administration, or a related role
- Proficiency in HRIS systems and Google applications
- Proactivity, curiosity and a strong drive/ initiative to explore new ideas and solutions
- Strong interest and enthusiasm for AI technologies, demonstrated by knowledge of current AI trends and practical experience using AI tools to enhance work processes
- Excellent attention to detail and strong organizational skills
- Ability to handle confidential information with discretion and professionalism
- Strong communication and interpersonal skills, with the ability to build relationships with employees at all levels
- Strong teamwork and customer service orientation to resolve issues quickly and accurately
- Solid understanding of HR processes and practices, with knowledge of employment laws and regulations
Expected Interview Process:
1) Recruiter Screen 2) Manager Screen/Tech Screen 3) Onsite 4) Offer
Expected Pay For This Role:
There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity
- Expected Helix Base: $72,000 - $104,250
- Expected Helix Discretionary Annual Bonus: 10% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.
Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
- Comprehensive Health Insurance with Date of Hire eligibility
- Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend
What To Expect During Your First 90 days:
- First 30 days: you’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
- Day 30 - 60: you’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.
- Day 60 - 90: you’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.
Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.
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Req ID: R739