About Us:

Eupraxia is a clinical-stage biotechnology company focused on developing locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. DiffuSphere™, a proprietary, polymer-based micro-sphere technology, is designed to facilitate targeted drug delivery of both existing and novel drugs. The technology is designed to support an extended duration of effect and delivery of drugs in a hyper-localized fashion, targeting only the tissues that physicians want to treat. We believe the potential for fewer adverse events may be achieved through the precision targeting and the stable and flat delivery of the active ingredient when using the DiffuSphere™ technology, versus the peaks and troughs seen with more traditional drug delivery methods. The precision of Eupraxia's DiffuSphere™ technology platform has the potential to augment and transform existing FDA-approved drugs to improve their safety, tolerability, efficacy and duration of effect. The potential uses in therapeutic areas extend beyond pain and inflammatory gastrointestinal disease, where Eupraxia is currently developing advanced treatments, to applications in oncology, infectious disease and other critical disease areas.

Eupraxia's EP-104GI is currently in a Phase 1b/2 trial (RESOLVE) for the treatment of eosinophilic esophagitis (EoE). EP-104GI is administered as an injection into the esophageal wall, providing local delivery of drug. This is a unique treatment approach for EoE. Eupraxia also recently completed a Phase 2b clinical trial (SPRINGBOARD) of EP-104IAR for the treatment of pain due to knee osteoarthritis. The SPRINGBOARD trial successfully met its primary endpoint and three of the four secondary endpoints. In addition, Eupraxia is developing a pipeline of later and earlier-stage long-acting formulations. Potential pipeline indications include candidates for other inflammatory joint indications and oncology, each designed to improve on the activity and tolerability of currently approved drugs. For further details about Eupraxia, please visit the Company's website at: www.eupraxiapharma.com.

Job Description:

Role Summary
Analytical Development Scientist is responsible for supporting technical operations related to analytical development and testing of sustained release drug products (polymer drug delivery systems). This includes analytical development, stability studies, data analysis, and documentation to support ongoing and new programs. This is an onsite position in Vancouver, and the scientist is required to perform laboratory development work.

Reports to: Associate Director, Analytical Chemistry

Key Responsibilities

• Support analytical development activities including initial lab assessments, method development, and troubleshooting
• Support stability programs including protocol drafting, report writing, and data trending
• Prepare and review analytical protocols and reports (validation, development, stability)
• Perform data analysis and interpretation to support development and regulatory activities
• Support coordination of analytical activities with CDMOs and internal teams
• Assist with SOP writing, revisions, and document lifecycle management
• Contribute to internal technical reports
• Routinely provide updates on analytical activities

Requirements

• 3–5 years experience in pharmaceutical industry
• PhD or MSc in Chemistry, Biochemistry, Chemical Engineering, or related field. Candidates with BSc plus relevant work experience will be considered
• Experience with analytical techniques such as HPLC (RP, SEC), Rheometer, Particle Size, USP Dissolution systems, thermal analysis, etc.
• Experience with analytical method development and validation in pharmaceutical industry
• Strong data analysis and technical writing skills
• Ability to manage multiple tasks in a fast-paced environment
• Familiarity with GMP and basic knowledge of ICH, FDA, and USP guidelines is an asset

Additional Attributes:

• Highly self motivated
• Ability to work independently and as part of a team
• Detail oriented and organized
• Accountable and proactive
• Strong communication skills
• A continuous learning mindset

Salary Range: $107,000 to $140,000 depending on education and relevant experience

Within the posted range, individual pay is determined by job related skills, relevant experience, education and/or training. Please note that the range details above reflect base pay only. A bonus will be available based on performance and remaining in post for the agreed contract duration. We also offer a competitive benefits package.

This is an opportunity to work in a small, entrepreneurial, and highly motivating environment, with strong exposure to analytical development and regulatory activities.