Job Description: Senior IT Manager

Location: South San Francisco, CA (Hybrid)
Reports to: Executive Director, Software and Data Systems
Department: Information Technology

About Cytovale

Cytovale is a medical diagnostics company focused on providing a faster, more insightful way to diagnose fast-moving and immune-mediated diseases. Cytovale’s IntelliSep test is the first and only stand-alone sepsis detection assay to quickly and accurately analyze white blood cell structure to stratify a patient’s risk of sepsis. The test simply and clearly shows the risk of sepsis using a biomechanical evaluation of white blood cells from a standard blood draw, generating results in less than 10 minutes.

For more information, please visit www.cytovale.com.

Role Overview

Cytovale is seeking a hands-on Senior IT Manager to lead day-to-day IT operations while helping build and scale the company’s internal IT capabilities for future growth. This role combines technical execution, operational leadership, strategic planning, and security-minded infrastructure management.

At this stage of growth, the Senior IT Manager will personally perform core systems administration and operational IT work, while also serving as a key partner to the Executive Director of Software & Data Systems in shaping IT strategy, roadmaps, governance, and scalable operating models.

The ideal candidate is equally comfortable resolving immediate operational needs, improving systems and processes, and planning for where the business is going next.

This role is ideal for someone who enjoys being in the tools, taking ownership end-to-end, and helping build a modern IT function in a growing healthcare technology company.

Key Responsibilities

IT Operations & Systems Administration

• Personally execute day-to-day IT operations and systems administration activities.

• Administer enterprise platforms including Microsoft 365, Azure, endpoint management, identity systems, and core business applications.

• Support cloud environments and operational tooling across platforms such as AWS and SaaS ecosystems.

• Perform employee onboarding/offboarding, access provisioning, device lifecycle management, and routine maintenance.

• Execute system upgrades, patching, and infrastructure improvements.

IT Strategy, Planning & Scaling

• Partner with the Executive Director of Software & Data Systems to develop Cytovale’s IT strategy and multi-year roadmap.

• Anticipate business growth needs and proactively evolve systems, tools, processes, and support models.

• Recommend scalable technology solutions that improve efficiency, security, and employee experience.

• Help define future organizational structure, staffing needs, and outsourced vs in-house operating models.

Security, Controls & Governance

• Maintain strong operational security posture across endpoints, identity systems, collaboration tools, and cloud environments.

• Support and help mature control frameworks such as SOC 2, HIPAA, and other relevant compliance standards.

• Implement and monitor IT security best practices including MFA, least privilege access, patch management, logging, backup, and lifecycle controls.

• Author, maintain, and improve IT policies, standards, and operational procedures.

• Participate in audits, evidence gathering, remediation tracking, and control improvements.

Operational Ownership & Service Delivery

• Own incident, request, and change management workflows to ensure timely service delivery.

• Define and improve SLAs, ticket workflows, escalation paths, and support performance metrics.

• Track and manage assets, software licensing, vendor renewals, and inventories.

• Build runbooks, documentation, and repeatable support processes.

MSP & Consultant Collaboration

• Partner with the Executive Director of Software & Data Systems in coordinating work with Cytovale’s IT MSP and external consultants.

• Help define priorities, review recommendations, and ensure strong execution from external partners.

• Hold vendors accountable to Cytovale’s standards for quality, responsiveness, security, and cost-effectiveness.

• Translate external recommendations into practical implementation plans.

Strategic Focus

• Reliable, secure, and scalable IT operations

• Strong security and control discipline

• Proactive planning ahead of business growth

• Excellent internal customer experience

• Building long-term IT maturity without unnecessary bureaucracy

Qualifications

Required

• 10+ years of experience in IT operations, systems administration, or IT infrastructure management

• Demonstrated success in a hands-on IT leadership role within a growing organization

• Strong experience administering Microsoft 365 and Azure environments

• Experience supporting or managing AWS and cloud-based systems

• Strong knowledge of modern IT security best practices and operational controls

• Experience supporting security/compliance frameworks such as SOC 2, HIPAA, ISO 27001, or similar

• Experience writing IT policies, standards, and operational procedures

• Experience working with MSPs, consultants, and external vendors

• Ability to balance strategic thinking with direct execution

Preferred

• Experience in healthcare, diagnostics, biotech, or regulated industries

• Familiarity with Intune, Entra ID, Defender, Vanta, ticketing systems, and endpoint tooling

• Experience scaling IT in a startup or growth-stage company

• Prior team leadership or people management experience

Cytovale Culture & What Great Looks Like Here

We’re looking for someone who will thrive in Cytovale’s environment, the ideal candidate will be:

• Comfortable with ambiguity: You can move forward without perfect information and adjust quickly as new data emerges.

• High ownership, low ego: You take accountability for outcomes, seek feedback, and care more about impact than credit.

• Execution-focused: you don’t just build strategies; you deliver results, iterate fast, and follow through.

• Intellectually curious: You enjoy digging into data, asking hard questions, and continuously improving your understanding.

• Resilient and adaptable: You stay steady and effective in a fast-paced, evolving environment.

• Mission-driven: You are motivated by Cytovale’s goal to improve outcomes for patients and want your work to matter.

What Success Looks Like in This Role

• IT operations run smoothly and reliably with minimal disruption

• Security controls and IT processes mature measurably over time

• Systems scale ahead of business demand rather than react behind it

• Employees receive responsive, high-quality IT support

• External partners are well-managed and productive

• Cytovale has a stronger, more scalable IT foundation one year from now